Abstract

Determining the optimum next-step treatment for the numerous patients with depression who do not adequately respond to an initial trial of medication remains a source of uncertainty in clinical practice.

Although a number of psychological treatments are known to be effective for depression, their relative merits in the treatment-resistant group have not been ascertained.

The Cochrane Collaboration has recently published a meta-analysis of the evidence available for the use of various psychotherapies as an adjunct to antidepressants compared with antidepressants alone in treatment-resistant depression.

This article provides a commentary and appraisal of the clinical utility of these findings.

Citations

Silman, D. (2020). How effective is augmentation with psychotherapy as a next-step option for treatment-resistant depression? BJPsych Advances, 26(5), 255-261

DOI: https://doi.org/10.1192/bja.2020.51

URI: https://www.oxfordhealth.nhs.uk/orka/title/how-effective-is-augmentation-with-psychotherapy-as-a-next-step-option-for-treatment-resistant-depression/